EUR-Lex. Access to European Union law "32002R0178" - “Regulation (EC) No 178/2002 of the European Parliament and of the Council of 28 January 2002 laying down the general principles and requirements of food law, establishing the European Food Safety Authority and laying down procedures in matters of food safety”.
make2pack.org - “Part 5 of the ISA-88 series of standards adds measurable business value by integrating manufacturing, packaging and enterprise information systems through international standards instead of custom programmiing”.
The “Escalation Management” is the linking platform for all other functional modules of a MES. There you can define “action control limits” and alarms, by which you can act rapidly in case of violation of limits. By this, the persistance of faulty states can be avoided and so the operating efficiency can be increased.